Respiratory tract antimicrobial peptides more effectively killed multiple methicillin-resistant Staphylococcus aureus and nontypeable Haemophilus influenzae isolates after disruption from biofilm residence

Respiratory tract antimicrobial peptides more effectively killed multiple methicillin-resistant Staphylococcus aureus and nontypeable Haemophilus influenzae isolates after disruption from biofilm residence

ABSTRACT Bacteria newly released (NRel) from biofilm residence via multiple methodologies are commonly significantly more sensitive to antibiotics. We’ve induced NRel with this phenotype after incubation of biofilms formed by diverse human pathogens with an epitope-targeted monoclonal antibody direc...

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Bibliographic Details
Main Authors: Nikola Kurbatfinski, Joseph A. Jurscisek, Kathryn Q. Wilbanks, Steven D. Goodman, Lauren O. Bakaletz
Format: Article
Language:English
Published: American Society for Microbiology 2025-08-01
Series:Microbiology Spectrum
Subjects:
DNABII
NRel
LL-37
cathelicidin
beta defensins
MRSA
Online Access:https://journals.asm.org/doi/10.1128/spectrum.03066-24
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