Is uric acid a true antioxidant? Identification of uric acid oxidation products and their biological effects

Is uric acid a true antioxidant? Identification of uric acid oxidation products and their biological effects

Uric acid (UA), the final product of purine metabolism in humans, exhibits a dual role as an anti or pro-oxidant, depending on the microenvironment. The two-electron oxidation of UA by biological oxidants can neutralize such harmful molecules. Additionally, UA chelates metals and can activate adapti...

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Bibliographic Details
Main Authors: Mikaela Peglow Pinz, Isadora Medeiros, Larissa Anastácio da Costa Carvalho, Flavia Carla Meotti
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:Redox Report
Subjects:
Uric acid
oxidation products
antioxidant
pro-oxidant
Online Access:https://www.tandfonline.com/doi/10.1080/13510002.2025.2498105
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https://www.tandfonline.com/doi/10.1080/13510002.2025.2498105

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