Predicting transmembrane helix packing arrangements using residue contacts and a force-directed algorithm.

Alpha-helical transmembrane proteins constitute roughly 30% of a typical genome and are involved in a wide variety of important biological processes including cell signalling, transport of membrane-impermeable molecules and cell recognition. Despite significant efforts to predict transmembrane prote...

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Bibliographic Details
Main Authors: Timothy Nugent, David T Jones
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-03-01
Series:PLoS Computational Biology
Online Access:https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1000714&type=printable
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