Regulation of autophagy by the PI3K-AKT pathway in Astragalus membranaceus -Cornus officinalis to ameliorate diabetic nephropathy

Regulation of autophagy by the PI3K-AKT pathway in Astragalus membranaceus -Cornus officinalis to ameliorate diabetic nephropathy

Aims and backgroundAutophagy plays an increasingly significant role in diabetic nephropathy (DN), but the mechanism by which autophagy participates in DN injury is not well understood. Our previous studies have shown that Astragalus membranaceus - Cornus officinalis (AM-CO) improves DN lipid metabol...

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Bibliographic Details
Main Authors:	Rui Zhang, Xushan Lan, Wenhui Zhu, Lifan Wang, Peng Liu, Ping Li
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-05-01
Series:	Frontiers in Pharmacology
Subjects:	diabetic nephropathy Astragalus membranaceus -Cornus officinalis calycosin lipidomic technology network analysis
Online Access:	https://www.frontiersin.org/articles/10.3389/fphar.2025.1505637/full
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