Molecular mechanisms underlying TXNIP’s anti-tumor role in breast cancer, including interaction with a novel, pro-tumor partner: CAST

Abstract Thioredoxin-interacting protein (TXNIP) plays a pivotal role in glucose metabolism and redox signaling. Its emerging function as a potent suppressor of cell proliferation in various cancer contexts underscores its importance in cancer development. In a previous study, we found TXNIP activat...

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Bibliographic Details
Main Authors: Jasvinder Singh, Bindeshwar Sah, Yibin Deng, Robert Clarke, Liang Liu
Format: Article
Language:English
Published: Nature Publishing Group 2025-04-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-025-07566-4
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