A practical guide to the interpretation of PK/PD profiles of longer-acting analogue insulins. Part two: Insulin degludec vs. insulin glargine U300

A practical guide to the interpretation of PK/PD profiles of longer-acting analogue insulins. Part two: Insulin degludec vs. insulin glargine U300

Glucose clamp studies form an integral part of the early development of insulin therapies. Data generated in these studies are used to establish pharmacokinetic (PK) and pharmacodynamic (PD) profiles of the agents, but methodological differences confound comparison of results from different glucose...

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Bibliographic Details
Main Authors: Oppel B.W. Greeff, Jacob John van Tonder, Kershlin Naidu, Alicia McMaster, Alet van Tonder, Rashem Mothilal
Format: Article
Language:English
Published: AOSIS 2018-08-01
Series:South African Family Practice
Subjects:
analogue insulins
glucose clamp
time–action profile
pharmacokinetics
pharmacodynamics
Online Access:https://safpj.co.za/index.php/safpj/article/view/4903
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