EFFICIENCY OF RECOMBINANT TNF-BINDING PROTEIN FROM VARIOLA VIRUS IN A MODEL OF COLLAGEN-INDUCED ARTHRITIS

EFFICIENCY OF RECOMBINANT TNF-BINDING PROTEIN FROM VARIOLA VIRUS IN A MODEL OF COLLAGEN-INDUCED ARTHRITIS

Abstract. This paper presents the results of the research on the effectiveness of recombinant TNF-binding protein of variola virus (VARV-CrmB) in a model of collagen-induced arthritis (CIA) in mice (CBAxC57Bl6) F1. The introduction of VARV-CrmB and polyclonal antibody to recombinant mouse TNF (poly-...

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Main Authors: D. D. Tsyrendorzhiev, S. V. Sennikov, I. A. Orlovskaya, I. P. Gileva, I. A. Ryazankin, L. B. Toporkova, V. V. Kurilin, Yu. A. Lopatnikova, A. A. Grydina, S. N. Schelkunov
Format: Article
Language:Russian
Published: St. Petersburg branch of the Russian Association of Allergologists and Clinical Immunologists 2014-07-01
Series:Медицинская иммунология
Subjects:
tumor necrosis factor
collagen
variola virus
leukocytes
rheumatoid arthritis
Online Access:https://www.mimmun.ru/mimmun/article/view/675
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