What does AlphaFold3 learn about antibody and nanobody docking, and what remains unsolved?

Antibody therapeutic development is a major focus in healthcare. To accelerate drug development, significant efforts have been directed toward the in silico design and screening of antibodies for which high modeling accuracy is necessary. To probe AlphaFold3’s (AF3) capabilities and limitations, we...

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Bibliographic Details
Main Authors: Fatima N. Hitawala, Jeffrey J. Gray
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:mAbs
Subjects:
Online Access:https://www.tandfonline.com/doi/10.1080/19420862.2025.2545601
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