Artificial intelligence accelerates the identification of nature-derived potent LOXL2 inhibitors

Abstract The role of LOXL2 in cancer has been widely demonstrated, but current therapies targeting LOXL2 are not yet fully developed. We believe that selective nature-derived inhibition of LOXL2 may provide a better therapeutic approach for the treatment of cancer. Therefore, we adopted a comprehens...

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Bibliographic Details
Main Authors: Xiaowei Jia, Meng Liu, Yushi Tang, Jingyan Meng, Ruolin Fang, Xiting Wang, Cheng Li
Format: Article
Language:English
Published: Nature Portfolio 2025-03-01
Series:Scientific Reports
Subjects:
Online Access:https://doi.org/10.1038/s41598-025-95530-9
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