Microbots: Transforming the treatment of oral cancer
Oral cancer incidence and mortality are high in India, Papua New Guinea, Taiwan, China, Eastern Europe, France, and parts of South America, where alcohol consumption and tobacco smoking are prevalent. Current oral cancer therapeutic techniques face limitations due to their inability to effectively t...
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| Format: | Article |
| Language: | English |
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KeAi Communications Co., Ltd.
2024-12-01
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| Series: | Nano TransMed |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2790676024000141 |
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| author | Gurudeva Chandrashekar Danis Vijay. D Gowtham Kumar Subbaraj |
| author_facet | Gurudeva Chandrashekar Danis Vijay. D Gowtham Kumar Subbaraj |
| author_sort | Gurudeva Chandrashekar |
| collection | DOAJ |
| description | Oral cancer incidence and mortality are high in India, Papua New Guinea, Taiwan, China, Eastern Europe, France, and parts of South America, where alcohol consumption and tobacco smoking are prevalent. Current oral cancer therapeutic techniques face limitations due to their inability to effectively target complex tumor locations and the associated adverse side effects. Microbots, tiny robots on a micrometre scale, offer a promising solution to these challenges. Microbots are constructed from biocompatible materials; these microbots can navigate the intricate mouth cavity and access deep tissues. Various agents, including fluorescent dyes for targeted tumor diagnosis, contrast agents for enhanced visualization in CT and MRI scans, and medicinal drugs, can equip them. The potential of microbots lies in their ability to specifically aggregate at tumor sites, which improves the efficacy of diagnostic agents and leads to more precise detection of oral cancer. Despite these difficulties, microbots provide a ground-breaking method for identifying oral cancer. Their ability to deliver diagnostic chemicals directly to the tumor site with minimal invasiveness has enormous potential for improving early identification and, eventually, patient outcomes. Large-scale clinical trials are required to demonstrate the safety and effectiveness of microbot assisted oral cancer diagnosis in humans. Further research is also necessary to create precise control mechanisms for microbot navigation within the mouth and optimal tumor site targeting. |
| format | Article |
| id | doaj-art-6837ed17c09942b2b2cf43e13a121d0c |
| institution | Kabale University |
| issn | 2790-6760 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | KeAi Communications Co., Ltd. |
| record_format | Article |
| series | Nano TransMed |
| spelling | doaj-art-6837ed17c09942b2b2cf43e13a121d0c2024-12-18T08:55:19ZengKeAi Communications Co., Ltd.Nano TransMed2790-67602024-12-013100043Microbots: Transforming the treatment of oral cancerGurudeva Chandrashekar0Danis Vijay. D1Gowtham Kumar Subbaraj2Department of Pharmacology, Karuna Medical College, Vilayodi, Chittur, Palakkad, Kerala 678103, IndiaDepartment of Microbiology, Karpaga Vinayaga Institute of Medical Sciences and Research Centre, Madhuranthagam, Chengalpattu, Tamil Nadu 603308, IndiaCorresponding author.; Faculty of Allied Health Sciences, Chettinad Hospital and Research Institute, Chettinad Academy of Research and Education (Deemed to be University), Old Mahabalipuram Road (OMR), Kelambakkam, Tamilnadu 603103, IndiaOral cancer incidence and mortality are high in India, Papua New Guinea, Taiwan, China, Eastern Europe, France, and parts of South America, where alcohol consumption and tobacco smoking are prevalent. Current oral cancer therapeutic techniques face limitations due to their inability to effectively target complex tumor locations and the associated adverse side effects. Microbots, tiny robots on a micrometre scale, offer a promising solution to these challenges. Microbots are constructed from biocompatible materials; these microbots can navigate the intricate mouth cavity and access deep tissues. Various agents, including fluorescent dyes for targeted tumor diagnosis, contrast agents for enhanced visualization in CT and MRI scans, and medicinal drugs, can equip them. The potential of microbots lies in their ability to specifically aggregate at tumor sites, which improves the efficacy of diagnostic agents and leads to more precise detection of oral cancer. Despite these difficulties, microbots provide a ground-breaking method for identifying oral cancer. Their ability to deliver diagnostic chemicals directly to the tumor site with minimal invasiveness has enormous potential for improving early identification and, eventually, patient outcomes. Large-scale clinical trials are required to demonstrate the safety and effectiveness of microbot assisted oral cancer diagnosis in humans. Further research is also necessary to create precise control mechanisms for microbot navigation within the mouth and optimal tumor site targeting.http://www.sciencedirect.com/science/article/pii/S2790676024000141MicrobotsOral cancerFluorescent dye-equipped microbotsMicrobots loaded with superparamagnetic iron oxide nanoparticlesLight-responsive microrobots |
| spellingShingle | Gurudeva Chandrashekar Danis Vijay. D Gowtham Kumar Subbaraj Microbots: Transforming the treatment of oral cancer Nano TransMed Microbots Oral cancer Fluorescent dye-equipped microbots Microbots loaded with superparamagnetic iron oxide nanoparticles Light-responsive microrobots |
| title | Microbots: Transforming the treatment of oral cancer |
| title_full | Microbots: Transforming the treatment of oral cancer |
| title_fullStr | Microbots: Transforming the treatment of oral cancer |
| title_full_unstemmed | Microbots: Transforming the treatment of oral cancer |
| title_short | Microbots: Transforming the treatment of oral cancer |
| title_sort | microbots transforming the treatment of oral cancer |
| topic | Microbots Oral cancer Fluorescent dye-equipped microbots Microbots loaded with superparamagnetic iron oxide nanoparticles Light-responsive microrobots |
| url | http://www.sciencedirect.com/science/article/pii/S2790676024000141 |
| work_keys_str_mv | AT gurudevachandrashekar microbotstransformingthetreatmentoforalcancer AT danisvijayd microbotstransformingthetreatmentoforalcancer AT gowthamkumarsubbaraj microbotstransformingthetreatmentoforalcancer |