Degradation of IRF6 by TRIM59 in tumor cells triggers PGM1-mediated glycolysis to regulate cell proliferation in neuroblastoma
Abstract Neuroblastoma is the most common extracranial malignancy in children, and patients who develop recurrent or metastatic disease are likely to have a much poorer survival prognosis. Herein, by applying random forest and XGBoost machine-learning techniques, we identified interferon regulatory...
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| Main Authors: | Liang Zeng, Hui Xu, Meng Li, Liang-Jun Qin, Kai Chen, Feng-Hua Wang, Xiaomin Li, Tianyou Yang, Lei Miao, Hai-Yun Wang |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Publishing Group
2025-08-01
|
| Series: | Cell Death and Disease |
| Online Access: | https://doi.org/10.1038/s41419-025-07932-2 |
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