Degradation of IRF6 by TRIM59 in tumor cells triggers PGM1-mediated glycolysis to regulate cell proliferation in neuroblastoma

Abstract Neuroblastoma is the most common extracranial malignancy in children, and patients who develop recurrent or metastatic disease are likely to have a much poorer survival prognosis. Herein, by applying random forest and XGBoost machine-learning techniques, we identified interferon regulatory...

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Bibliographic Details
Main Authors: Liang Zeng, Hui Xu, Meng Li, Liang-Jun Qin, Kai Chen, Feng-Hua Wang, Xiaomin Li, Tianyou Yang, Lei Miao, Hai-Yun Wang
Format: Article
Language:English
Published: Nature Publishing Group 2025-08-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-025-07932-2
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