Effective treatment of refractory, locally metastatic squamous cell carcinoma of the leg with isolated limb perfusion: a case report with unexpected long progression-free interval

Effective treatment of refractory, locally metastatic squamous cell carcinoma of the leg with isolated limb perfusion: a case report with unexpected long progression-free interval

Non-melanoma skin cancer (NMSC) is one of the most commonly diagnosed human malignancies and its incidence is steadily increasing. Locally advanced cutaneous squamous cell carcinoma of the extremities that is refractory to standard therapies can be challenging to treat, with amputation of the limb b...

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Bibliographic Details
Main Authors: Danai-Dionysia Kanatoula, Sebastian A. Wohlfeil, Jens Jakob, Peter Hohenberger, Jochen Utikal
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-03-01
Series:Frontiers in Oncology
Subjects:
SCC
squamous cell carcinoma
treatment
isolated limb perfusion
rhTNFα
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2025.1549683/full
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