Molecular-genetic mechanisms of the signal cascade RAS-RAF-MEK-ERK associated with the development of the tumor process and the purpose of targeted drugs for colorectal cancer
Colorectal cancer occupies one of the leading positions in the world in the structure of cancer incidence. The vital processes of cancer cells largely depend on the production of growth factors and their receptors. One of these is epidermal growth factor (EGFR), which is a tyrosine kinase receptor f...
Saved in:
| Main Authors: | A. N. Toropovsky, O. N. Pavlova, D. A. Viktorov, A. G. Nikitin |
|---|---|
| Format: | Article |
| Language: | Russian |
| Published: |
Private institution educational organization of higher education "Medical University "ReaViz"
2021-08-01
|
| Series: | Вестник медицинского института «Реавиз»: Реабилитация, врач и здоровье |
| Subjects: | |
| Online Access: | https://vestnik.reaviz.ru/jour/article/view/279 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
The complex journey of targeting RAS in oncology
by: Katarzyna Wasiak, et al.
Published: (2025-07-01) -
A diaryl urea derivative, SMCl inhibits cell proliferation through the RAS/RAF/MEK/ERK pathway in hepatocellular carcinoma
by: Yue Fu, et al.
Published: (2025-07-01) -
Dayuan Yin alleviates symptoms of HCoV-229E-induced pneumonia and modulates the Ras/Raf1/MEK/ERK pathway
by: Rui Li, et al.
Published: (2024-11-01) -
The role of KRAS and NRAS mutation detection in determining the therapy strategy for colorectal cancer
by: A. N. Toropovskiy, et al.
Published: (2022-11-01) -
The opposite association of HRAS and KRAS mutations with clinical variables of bladder cancer
by: M. P. Smal, et al.
Published: (2015-12-01)