In-silico drug repositioning studies of Candida albicans Nitrogen permease reactivator 1 (Npr1) kinase

In-silico drug repositioning studies of Candida albicans Nitrogen permease reactivator 1 (Npr1) kinase

Abstract Npr1 is an essential protein in C. albicans, maintains ion homeostasis and nutrient transportation at cell membrane, and regulates the activity of ammonium transporter protein Mep2. Npr1 is one of the nine NPR/HAL family kinases classified under “Other groups” in C. albicans. In this study,...

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Main Authors: Sanjib Das, Arka Bagchi, Analava Bera, Arunima Biswas, Analabha Roy, Rik Ganguly, Amalesh Mondal, Deepanjan Chattopadhyay, Paromita Saha Mondal, Tanushree Mondal, Subhasree Samanta, Achintya Mohan Goswami, Tanima Saha
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
Candida albicans
Nitrogen permease reactivator 1
Indacaterol
Drug-repositioning
Online Access:https://doi.org/10.1038/s41598-025-08148-2
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