Mechanism study on the treatment of ulcerative colitis by Gegen Qinlian nano-preparation through promoting M2 macrophage polarization

Mechanism study on the treatment of ulcerative colitis by Gegen Qinlian nano-preparation through promoting M2 macrophage polarization

ObjectiveTo address the core pathological features of intestinal barrier disruption and immune imbalance in ulcerative colitis (UC), we developed a nano-targeted formulation (GGQL nano-preparation) based on berberine, puerarin, baicalin, and glycyrrhizin by combining traditional Chinese medicine (TC...

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Main Authors: Jilei Li, Jiarui Cao, Zhenyu Zhang, Sizhe Wang, Meng Zhu, Lili Yang, Wenhui Ouyang, Chunzheng Ma
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-04-01
Series:Frontiers in Molecular Biosciences
Subjects:
ulcerative colitis
Gegen Qinlian nano-preparation
nanoparticle-targeted traditional Chinese medicine
macrophages
polarization
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2025.1580874/full
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