The Effects of Exercise Training Interventions on Dialysis Patients: A Narrative Review of Current Knowledge and Future Perspectives

Chronic diseases are a growing concern in aging populations, with physical inactivity playing a major role in their onset and progression. Chronic kidney disease (CKD), which affects approximately 15% of U.S. adults and over 500 million people worldwide, is strongly associated with sedentary behavio...

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Bibliographic Details
Main Authors: Claudia Torino, Giovanni Tripepi, Francesca Mallamaci
Format: Article
Language:English
Published: MDPI AG 2025-06-01
Series:Kidney and Dialysis
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Online Access:https://www.mdpi.com/2673-8236/5/2/25
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Summary:Chronic diseases are a growing concern in aging populations, with physical inactivity playing a major role in their onset and progression. Chronic kidney disease (CKD), which affects approximately 15% of U.S. adults and over 500 million people worldwide, is strongly associated with sedentary behavior. Despite mounting evidence supporting the benefits of exercise training in CKD management, current treatment approaches remain largely pharmacological, with exercise interventions receiving limited emphasis. One challenge is the uncertainty surrounding the most appropriate exercise modalities for CKD patients, particularly those undergoing dialysis. Recent guidelines from leading nephrology organizations advocate for integrating exercise training into CKD care, recommending at least 150 min of moderate-intensity exercise per week. This narrative review examines clinical studies on exercise interventions in dialysis patients, highlighting their impact on health outcomes and quality of life. Additionally, it explores the physiological mechanisms underlying these benefits and assesses nephrologists’ perspectives on prescribing exercise training. By addressing these critical aspects, this review aims to underscore the necessity of incorporating exercise into CKD treatment strategies.
ISSN:2673-8236