Saliva proteins of vector Culicoides modify structure and infectivity of bluetongue virus particles.

Saliva proteins of vector Culicoides modify structure and infectivity of bluetongue virus particles.

Bluetongue virus (BTV) and epizootic haemorrhagic disease virus (EHDV) are related orbiviruses, transmitted between their ruminant hosts primarily by certain haematophagous midge vectors (Culicoides spp.). The larger of the BTV outer-capsid proteins, 'VP2', can be cleaved by proteases (inc...

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Bibliographic Details
Main Authors: Karin E Darpel, Kathrin F A Langner, Manfred Nimtz, Simon J Anthony, Joe Brownlie, Haru-Hisa Takamatsu, Philip S Mellor, Peter P C Mertens
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-03-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0017545&type=printable
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