Development of a more efficient catalyst for the redox-neutral organocatalytic mitsunobu reaction by DFT-guided catalyst design

Development of a more efficient catalyst for the redox-neutral organocatalytic mitsunobu reaction by DFT-guided catalyst design

The study of a Mitsunobu reaction is an important topic. Denton and co-workers first reported a novel (2-hydroxybenzyl)diphenylphosphine oxide for realizing the catalytic Mitsunobu reaction via a five-membered phosphonium species. However, it is still worth investigating how to improve catalysts wit...

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Bibliographic Details
Main Authors: Dingguo Song, Changjun Zhang, Yuqi Cheng, Linlin Chen, Jie Lin, Changdi Zheng, Ting Liu, Yuxin Ding, Fei Ling, Weihui Zhong
Format: Article
Language:English
Published: KeAi Communications Co. Ltd. 2024-11-01
Series:Green Synthesis and Catalysis
Subjects:
Phosphine oxide
Mitsunobu reaction
Late-sFtage diversification
Drug discovery process
Online Access:http://www.sciencedirect.com/science/article/pii/S2666554923000844
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