Synergistic effects of fluorinated substituents and Fe(Ⅱ) on ferrihydrite transformation and antibiotic degradation
Ferrihydrite is commonly associated with antibiotics in natural environments due to its strong sorption capabilities and high specific surface area. Under reducing conditions, Fe(II) acts as a catalyst for the transformation of ferrihydrite into more crystalline minerals. However, the influence of a...
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Elsevier
2025-06-01
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| Series: | Ecotoxicology and Environmental Safety |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S0147651325006499 |
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| author | Liting Wang Shikun Wei Liwen Zhang Zhiyong Guo Yan Lei Deming Dong |
| author_facet | Liting Wang Shikun Wei Liwen Zhang Zhiyong Guo Yan Lei Deming Dong |
| author_sort | Liting Wang |
| collection | DOAJ |
| description | Ferrihydrite is commonly associated with antibiotics in natural environments due to its strong sorption capabilities and high specific surface area. Under reducing conditions, Fe(II) acts as a catalyst for the transformation of ferrihydrite into more crystalline minerals. However, the influence of antibiotic molecular structure on the Fe(II)-catalyzed transformation of ferrihydrite and the associated degradation mechanisms of antibiotics have remained unclear. This study employed enoxacin (ENO), a representative fluorinated pharmaceutical, and pipemidic acid (PPA), a structural analog of ENO, to investigate the effect of fluorinated substituents on Fe(II)-facilitated ferrihydrite transformation. The results revealed that the transformation of ferrihydrite in the ENO system was 2.8 times greater than in the PPA system. ENO degradation reached 74.3 %, which was 1.13 times higher than that of PPA. ENO degradation products were more prone to hydroxylation, decarboxylation, and piperazine ring oxidation, whereas PPA degradation primarily involved oxidation of the piperazine ring. The fluorinated substituent in ENO facilitated ferrihydrite transformation by influencing the concentration of adsorbed Fe(II) and the distribution of antibiotics within the mineral inside. Furthermore, the fluorinated substituent in ENO enhanced degradation by increasing electron transfer between ENO and Fe(III), raising the content of adsorbed Fe(II) and promoting the formation of goethite. Collectively, these findings provide new insights into the environmental behavior of ferrihydrite and the fate of structurally different antibiotics in natural systems. |
| format | Article |
| id | doaj-art-47c3e4ee48ad4398a0c7dae52b79a7d7 |
| institution | DOAJ |
| issn | 0147-6513 |
| language | English |
| publishDate | 2025-06-01 |
| publisher | Elsevier |
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| series | Ecotoxicology and Environmental Safety |
| spelling | doaj-art-47c3e4ee48ad4398a0c7dae52b79a7d72025-08-20T03:13:30ZengElsevierEcotoxicology and Environmental Safety0147-65132025-06-0129811831310.1016/j.ecoenv.2025.118313Synergistic effects of fluorinated substituents and Fe(Ⅱ) on ferrihydrite transformation and antibiotic degradationLiting Wang0Shikun Wei1Liwen Zhang2Zhiyong Guo3Yan Lei4Deming Dong5Key Laboratory of Groundwater Resources and Environment, Ministry of Education, Jilin Provincial Key Laboratory of Water Resources and Environment, College of New Energy and Environment, Jilin University, Changchun 130012, China; School of Materials and Environmental Engineering, Chengdu Technological University, Chengdu, Sichuan 610031, ChinaKey Laboratory of Groundwater Resources and Environment, Ministry of Education, Jilin Provincial Key Laboratory of Water Resources and Environment, College of New Energy and Environment, Jilin University, Changchun 130012, ChinaKey Laboratory of Groundwater Resources and Environment, Ministry of Education, Jilin Provincial Key Laboratory of Water Resources and Environment, College of New Energy and Environment, Jilin University, Changchun 130012, ChinaKey Laboratory of Groundwater Resources and Environment, Ministry of Education, Jilin Provincial Key Laboratory of Water Resources and Environment, College of New Energy and Environment, Jilin University, Changchun 130012, China; Corresponding authors.School of Materials and Environmental Engineering, Chengdu Technological University, Chengdu, Sichuan 610031, China; Corresponding authors.Key Laboratory of Groundwater Resources and Environment, Ministry of Education, Jilin Provincial Key Laboratory of Water Resources and Environment, College of New Energy and Environment, Jilin University, Changchun 130012, ChinaFerrihydrite is commonly associated with antibiotics in natural environments due to its strong sorption capabilities and high specific surface area. Under reducing conditions, Fe(II) acts as a catalyst for the transformation of ferrihydrite into more crystalline minerals. However, the influence of antibiotic molecular structure on the Fe(II)-catalyzed transformation of ferrihydrite and the associated degradation mechanisms of antibiotics have remained unclear. This study employed enoxacin (ENO), a representative fluorinated pharmaceutical, and pipemidic acid (PPA), a structural analog of ENO, to investigate the effect of fluorinated substituents on Fe(II)-facilitated ferrihydrite transformation. The results revealed that the transformation of ferrihydrite in the ENO system was 2.8 times greater than in the PPA system. ENO degradation reached 74.3 %, which was 1.13 times higher than that of PPA. ENO degradation products were more prone to hydroxylation, decarboxylation, and piperazine ring oxidation, whereas PPA degradation primarily involved oxidation of the piperazine ring. The fluorinated substituent in ENO facilitated ferrihydrite transformation by influencing the concentration of adsorbed Fe(II) and the distribution of antibiotics within the mineral inside. Furthermore, the fluorinated substituent in ENO enhanced degradation by increasing electron transfer between ENO and Fe(III), raising the content of adsorbed Fe(II) and promoting the formation of goethite. Collectively, these findings provide new insights into the environmental behavior of ferrihydrite and the fate of structurally different antibiotics in natural systems.http://www.sciencedirect.com/science/article/pii/S0147651325006499Fluorinated substituentAntibioticTransformationFerrihydriteGoethite |
| spellingShingle | Liting Wang Shikun Wei Liwen Zhang Zhiyong Guo Yan Lei Deming Dong Synergistic effects of fluorinated substituents and Fe(Ⅱ) on ferrihydrite transformation and antibiotic degradation Ecotoxicology and Environmental Safety Fluorinated substituent Antibiotic Transformation Ferrihydrite Goethite |
| title | Synergistic effects of fluorinated substituents and Fe(Ⅱ) on ferrihydrite transformation and antibiotic degradation |
| title_full | Synergistic effects of fluorinated substituents and Fe(Ⅱ) on ferrihydrite transformation and antibiotic degradation |
| title_fullStr | Synergistic effects of fluorinated substituents and Fe(Ⅱ) on ferrihydrite transformation and antibiotic degradation |
| title_full_unstemmed | Synergistic effects of fluorinated substituents and Fe(Ⅱ) on ferrihydrite transformation and antibiotic degradation |
| title_short | Synergistic effects of fluorinated substituents and Fe(Ⅱ) on ferrihydrite transformation and antibiotic degradation |
| title_sort | synergistic effects of fluorinated substituents and fe ii on ferrihydrite transformation and antibiotic degradation |
| topic | Fluorinated substituent Antibiotic Transformation Ferrihydrite Goethite |
| url | http://www.sciencedirect.com/science/article/pii/S0147651325006499 |
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