Assessment of the transmission of live-attenuated chikungunya virus vaccine VLA1553 by Aedes albopictus mosquitoes

Assessment of the transmission of live-attenuated chikungunya virus vaccine VLA1553 by Aedes albopictus mosquitoes

Abstract Background Chikungunya virus (CHIKV) is a mosquito-transmitted, arthritogenic alphavirus that causes sporadic outbreaks of often debilitating rheumatic disease. The recently approved CHIKV vaccine, IXCHIQ, is based on a live-attenuated CHIKV strain (VLA1553), with viraemic vaccine recipient...

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Bibliographic Details
Main Authors: Andrea Fritzer, Andreas Suhrbier, Leon E. Hugo, Bing Tang, Greg Devine, Sandra Jost, Andreas L. Meinke
Format: Article
Language:English
Published: BMC 2025-05-01
Series:Parasites & Vectors
Subjects:
Alphavirus
Chikungunya
IXCHIQ
VLA1553
Mosquito
Transmission
Online Access:https://doi.org/10.1186/s13071-025-06789-w
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