Locally producing antibacterial peptide to deplete intratumoral pathogen for preventing metastatic breast cancer

Locally producing antibacterial peptide to deplete intratumoral pathogen for preventing metastatic breast cancer

Metastatic dissemination is the major cause of death from breast-cancer (BC). Fusobacterium nucleatum (F.n) is widely enriched in BC and has recently been identified as one of the high-risk factors for promoting BC metastasis. Here, with an experimental model, we demonstrated that intratumoral F.n i...

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Bibliographic Details
Main Authors: Shizhen Geng, Tingting Xiang, Yaru Shi, Mengnian Cao, Danyu Wang, Jing Wang, Xinling Li, Haiwei Song, Zhenzhong Zhang, Jinjin Shi, Junjie Liu, Airong Li, Ke Sun
Format: Article
Language:English
Published: Elsevier 2025-02-01
Series:Acta Pharmaceutica Sinica B
Subjects:
Intratumoral pathogen
Metastasis
Antibacterial peptide
Optogenetics
Breast cancer
Fusobacterium nucleatum
Online Access:http://www.sciencedirect.com/science/article/pii/S221138352500005X
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