L-serine-O-sulfate alters cellular ultrastructure and mitigates the capacity of biofilm formation in Streptococcus mutans UA159 via interfering with glutamate racemase

L-serine-O-sulfate alters cellular ultrastructure and mitigates the capacity of biofilm formation in Streptococcus mutans UA159 via interfering with glutamate racemase

Dental caries, primarily caused by Streptococcus mutans (S. mutans), remains a significant global health challenge. Conventional treatments often disrupt commensal oral flora, necessitating targeted antimicrobial strategies. This study investigated L‑serine-O-sulfate (LSOS), a substrate analog of gl...

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Bibliographic Details
Main Authors: Jianying Zhang, He-Ling Wang, Tianyu Ding, Yingjie Sun, Shaotai Wang, Chengcheng Yin
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Current Research in Microbial Sciences
Subjects:
Dental caries
Streptococcus mutans UA159
Glutamate racemase
Substrate analog
Antimicrobial agent
Biosafety
Online Access:http://www.sciencedirect.com/science/article/pii/S2666517425000896
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