EPHX1 and ERCC2 polymorphisms are associated with cisplatin-induced nephrotoxicity and prognosis in Thai cancer patients.

EPHX1 and ERCC2 polymorphisms are associated with cisplatin-induced nephrotoxicity and prognosis in Thai cancer patients.

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Cisplatin is a widely used chemotherapeutic drug for various cancers. One of the common adverse effects of cisplatin is nephrotoxicity including acute kidney injury (AKI) and acute kidney disease (AKD). Single Nucleotide Polymorphisms (SNPs) can be used to identify cancer patients who are susceptibl...

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Main Authors: Saad Ahmed, Jakris Eu-Ahsunthornwattana, Thanaporn Thamrongjirapat, Aruchalean Taweewongsounton, Yutthana Rittavee, Nintita Sripaiboonkit Thokanit, Montien Ngodngamthaweesuk, Pitichote Hiranyatheb, Thanyanan Reungwetwattana, Nuttapong Ngamphaiboon, Natini Jinawath
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0324699
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