Transcriptomics of tissue exosomes to investigate miR-195-5p’s amelioration of endometrial fibrosis via the YAP-Smad7 pathway: an animal study

Transcriptomics of tissue exosomes to investigate miR-195-5p’s amelioration of endometrial fibrosis via the YAP-Smad7 pathway: an animal study

Abstract Background A significant research gap exists regarding the role of tissue exosomes in intrauterine adhesions (IUAs). This study aims to investigate the involvement of miR-195-5p and its regulatory network in IUAs through the analysis of tissue exosomes. Methods Exosomes from rat uterine tis...

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Bibliographic Details
Main Authors: Jia-ming Chen, Qiao-yi Huang, Wei-hong Chen, Jin-xiang Wu, Ling-tao Zheng, Hui-jie You, Yan-chuan Shi, Shu Lin, Qi-rong Shi
Format: Article
Language:English
Published: BMC 2024-11-01
Series:Journal of Translational Medicine
Subjects:
Tissue exosomes
miR-195-5p
Intrauterine adhesion
Myofibroblast transdifferentiation
YAP–Smad7
Hippo pathway
Online Access:https://doi.org/10.1186/s12967-024-05871-8
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https://doi.org/10.1186/s12967-024-05871-8

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