Efficacy and safety of minocycline in retinitis pigmentosa: a prospective, open-label, single-arm trial

Efficacy and safety of minocycline in retinitis pigmentosa: a prospective, open-label, single-arm trial

Abstract Retinitis pigmentosa (RP) is characterized by progressive photoreceptor cells death accelerated by the proliferation and activation of microglia pathologically. No consensus exists on the treatment. Minocycline is recognized as a microglia inhibitor with great anti-inflammatory and neuro-pr...

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Main Authors: Yuxi Chen, Yuan Pan, Yanyan Xie, Yuxun Shi, Yao Lu, Yiwen Xia, Wenru Su, Xiaoqing Chen, Zuoyi Li, Minzhen Wang, Siyu Miao, Yating Yang, Chenjin Jin, Guangwei Luo, Shixian Long, Hui Xiao, Chuangxin Huang, Jian Zhang, Dan Liang
Format: Article
Language:English
Published: Nature Publishing Group 2024-12-01
Series:Signal Transduction and Targeted Therapy
Online Access:https://doi.org/10.1038/s41392-024-02037-2
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https://doi.org/10.1038/s41392-024-02037-2

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