Group Interpersonal Psychotherapy in Patients with Treatment Resistant Depression: A Qualitative Analysis

Depressive disorders are a worldwide leading cause of health-related burden, and a subgroup of depression patients fail to respond to available psychopharmacological treatments, a condition called Treatment Resistant Depression (TRD). While evidence suggests that both traditional and group (IPT-G) I...

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Main Authors: Maria Isabel Perez Mattos, Daniela Knauth, Anna Viduani, Scott Stuart, Bruno Paz Mosqueiro, Marco Antonio Caldieraro, Laura Wolf de Souza, Ariane Gusmão Chini, Rachel Santos Nery, Manoella Pestana Lopes, Marcelo P. Fleck
Format: Article
Language:English
Published: SAGE Publishing 2024-12-01
Series:SAGE Open
Online Access:https://doi.org/10.1177/21582440241288105
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author Maria Isabel Perez Mattos
Daniela Knauth
Anna Viduani
Scott Stuart
Bruno Paz Mosqueiro
Marco Antonio Caldieraro
Laura Wolf de Souza
Ariane Gusmão Chini
Rachel Santos Nery
Manoella Pestana Lopes
Marcelo P. Fleck
author_facet Maria Isabel Perez Mattos
Daniela Knauth
Anna Viduani
Scott Stuart
Bruno Paz Mosqueiro
Marco Antonio Caldieraro
Laura Wolf de Souza
Ariane Gusmão Chini
Rachel Santos Nery
Manoella Pestana Lopes
Marcelo P. Fleck
author_sort Maria Isabel Perez Mattos
collection DOAJ
description Depressive disorders are a worldwide leading cause of health-related burden, and a subgroup of depression patients fail to respond to available psychopharmacological treatments, a condition called Treatment Resistant Depression (TRD). While evidence suggests that both traditional and group (IPT-G) Interpersonal Psychotherapy interventions are efficient treatments for depression, few studies have evaluated the effect of IPT on TRD. Qualitatively analyze an IPT-G intervention conducted with TRD patients using a deductive, theory informed approach, to explore how TDR patients understand, contextualize and apply IPT’s problem-areas throughout the course of the treatment. 10 IPT-G sessions were analyzed using Framework Analysis. Sessions were video recorded and transcribed verbatim, and participants’ accounts were coded with predetermined, conceptually derived codes that were based on the three main problem areas identified in IPT. Following IPT’s main problem areas, three themes were generated: “Mechanisms of change—Improving communication”; “Acceptance of loss”; and “Finding new roles—depression, role transition, and reclaiming life conditions.” Our analysis suggests that patients with TRD can benefit from IPT-G. Depression is seen as a chronic condition that deeply affects the lives of patients, and IPT-G was seen as a way of promoting change and regaining control. However, we identified that patients to whom IPT-G did not achieve the same effect in terms of symptom reduction have greater difficulty in acquiring and generalizing new interpersonal skills, and often were immersed in severe family or marital interpersonal disputes.
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spelling doaj-art-35ae8fb7cde1456d8efa12917bca8b3b2025-08-20T01:56:38ZengSAGE PublishingSAGE Open2158-24402024-12-011410.1177/21582440241288105Group Interpersonal Psychotherapy in Patients with Treatment Resistant Depression: A Qualitative AnalysisMaria Isabel Perez Mattos0Daniela Knauth1Anna Viduani2Scott Stuart3Bruno Paz Mosqueiro4Marco Antonio Caldieraro5Laura Wolf de Souza6Ariane Gusmão Chini7Rachel Santos Nery8Manoella Pestana Lopes9Marcelo P. Fleck10Hospital de Clínicas de Porto Alegre, BrazilHospital de Clínicas de Porto Alegre, BrazilHospital de Clínicas de Porto Alegre, BrazilUniversity of Southern California, Los Angeles, USAHospital de Clínicas de Porto Alegre, BrazilHospital de Clínicas de Porto Alegre, BrazilHospital de Clínicas de Porto Alegre, BrazilHospital de Clínicas de Porto Alegre, BrazilHospital de Clínicas de Porto Alegre, BrazilHospital de Clínicas de Porto Alegre, BrazilHospital de Clínicas de Porto Alegre, BrazilDepressive disorders are a worldwide leading cause of health-related burden, and a subgroup of depression patients fail to respond to available psychopharmacological treatments, a condition called Treatment Resistant Depression (TRD). While evidence suggests that both traditional and group (IPT-G) Interpersonal Psychotherapy interventions are efficient treatments for depression, few studies have evaluated the effect of IPT on TRD. Qualitatively analyze an IPT-G intervention conducted with TRD patients using a deductive, theory informed approach, to explore how TDR patients understand, contextualize and apply IPT’s problem-areas throughout the course of the treatment. 10 IPT-G sessions were analyzed using Framework Analysis. Sessions were video recorded and transcribed verbatim, and participants’ accounts were coded with predetermined, conceptually derived codes that were based on the three main problem areas identified in IPT. Following IPT’s main problem areas, three themes were generated: “Mechanisms of change—Improving communication”; “Acceptance of loss”; and “Finding new roles—depression, role transition, and reclaiming life conditions.” Our analysis suggests that patients with TRD can benefit from IPT-G. Depression is seen as a chronic condition that deeply affects the lives of patients, and IPT-G was seen as a way of promoting change and regaining control. However, we identified that patients to whom IPT-G did not achieve the same effect in terms of symptom reduction have greater difficulty in acquiring and generalizing new interpersonal skills, and often were immersed in severe family or marital interpersonal disputes.https://doi.org/10.1177/21582440241288105
spellingShingle Maria Isabel Perez Mattos
Daniela Knauth
Anna Viduani
Scott Stuart
Bruno Paz Mosqueiro
Marco Antonio Caldieraro
Laura Wolf de Souza
Ariane Gusmão Chini
Rachel Santos Nery
Manoella Pestana Lopes
Marcelo P. Fleck
Group Interpersonal Psychotherapy in Patients with Treatment Resistant Depression: A Qualitative Analysis
SAGE Open
title Group Interpersonal Psychotherapy in Patients with Treatment Resistant Depression: A Qualitative Analysis
title_full Group Interpersonal Psychotherapy in Patients with Treatment Resistant Depression: A Qualitative Analysis
title_fullStr Group Interpersonal Psychotherapy in Patients with Treatment Resistant Depression: A Qualitative Analysis
title_full_unstemmed Group Interpersonal Psychotherapy in Patients with Treatment Resistant Depression: A Qualitative Analysis
title_short Group Interpersonal Psychotherapy in Patients with Treatment Resistant Depression: A Qualitative Analysis
title_sort group interpersonal psychotherapy in patients with treatment resistant depression a qualitative analysis
url https://doi.org/10.1177/21582440241288105
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