Clonal expansion within pneumococcal serotype 6C after use of seven-valent vaccine.

Clonal expansion within pneumococcal serotype 6C after use of seven-valent vaccine.

Streptococcus pneumoniae causes invasive infections, primarily at the extremes of life. A seven-valent conjugate vaccine (PCV7) is used to protect against invasive pneumococcal disease in children. Within three years of PCV7 introduction, we observed a fourfold increase in serotype 6C carriage, pred...

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Bibliographic Details
Main Authors: Nicholas J Loman, Rebecca A Gladstone, Chrystala Constantinidou, Anna S Tocheva, Johanna M C Jefferies, Saul N Faust, Leigh O'Connor, Jacqueline Chan, Mark J Pallen, Stuart C Clarke
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0064731&type=printable
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