The organ-protective effects of nitric oxide in adult patients undergoing cardiac surgery with cardiopulmonary bypass: a systematic review and meta-analysis

The organ-protective effects of nitric oxide in adult patients undergoing cardiac surgery with cardiopulmonary bypass: a systematic review and meta-analysis

Abstract Background Postoperative organ dysfunction remains a major challenge in adult cardiac surgery with cardiopulmonary bypass (CPB), frequently involving the kidneys, heart, and lungs. These complications are primarily driven by hemolysis, ischemia-reperfusion injury, and systemic inflammation...

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Bibliographic Details
Main Authors: Jieru Zhang, Han Zhang, Jing Wang, Tianlong Wang, Luyu Bian, Zhenzhen Li, Jian Wang, Yuan Teng, Gang Liu, Shujie Yan, Bingyang Ji
Format: Article
Language:English
Published: BMC 2025-07-01
Series:BMC Anesthesiology
Subjects:
Nitric oxide
Cardiac surgery
Cardiopulmonary bypass
Acute kidney injury
Organ-protection
Online Access:https://doi.org/10.1186/s12871-025-03207-7
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