Chikungunya virus in Asia – Pacific: a systematic review
Chikungunya virus (CHIKV) is a mosquito-borne pathogen that causes an acute febrile syndrome and severe, debilitating rheumatic disorders in humans that may persist for months. CHIKV’s presence in Asia dates from at least 1954, but its epidemiological profile in the region remains poorly understood....
Saved in:
| Main Authors: | , , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Taylor & Francis Group
2019-01-01
|
| Series: | Emerging Microbes and Infections |
| Subjects: | |
| Online Access: | https://www.tandfonline.com/doi/10.1080/22221751.2018.1559708 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849702717724819456 |
|---|---|
| author | B. M. C. Randika Wimalasiri-Yapa Liesel Stassen Xiaodong Huang Louise M. Hafner Wenbiao Hu Gregor J. Devine Laith Yakob Cassie C. Jansen Helen M. Faddy Elvina Viennet Francesca D. Frentiu |
| author_facet | B. M. C. Randika Wimalasiri-Yapa Liesel Stassen Xiaodong Huang Louise M. Hafner Wenbiao Hu Gregor J. Devine Laith Yakob Cassie C. Jansen Helen M. Faddy Elvina Viennet Francesca D. Frentiu |
| author_sort | B. M. C. Randika Wimalasiri-Yapa |
| collection | DOAJ |
| description | Chikungunya virus (CHIKV) is a mosquito-borne pathogen that causes an acute febrile syndrome and severe, debilitating rheumatic disorders in humans that may persist for months. CHIKV’s presence in Asia dates from at least 1954, but its epidemiological profile in the region remains poorly understood. We systematically reviewed CHIKV emergence, epidemiology, clinical features, atypical manifestations and distribution of virus genotypes, in 47 countries from South East Asia (SEA) and the Western Pacific Region (WPR) during the period 1954–2017. Following the Cochrane Collaboration guidelines, Pubmed and Scopus databases, surveillance reports available in the World Health Organisation (WHO) and government websites were systematically reviewed. Of the 3504 records identified, 461 were retained for data extraction. Although CHIKV has been circulating in Asia almost continuously since the 1950s, it has significantly expanded its geographic reach in the region from 2005 onwards. Most reports identified in the review originated from India. Although all ages and both sexes can be affected, younger children and the elderly are more prone to severe and occasionally fatal forms of the disease, with child fatalities recorded since 1963 from India. The most frequent clinical features identified were arthralgia, rash, fever and headache. Both the Asian and East-Central-South African (ECSA) genotypes circulate in SEA and WPR, with ECSA genotype now predominant. Our findings indicate a substantial but poorly documented burden of CHIKV infection in the Asia-Pacific region. An evidence-based consensus on typical clinical features of chikungunya could aid in enhanced diagnosis and improved surveillance of the disease. |
| format | Article |
| id | doaj-art-2c74df388ccd4c65b2eeb1750e9646e2 |
| institution | DOAJ |
| issn | 2222-1751 |
| language | English |
| publishDate | 2019-01-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Emerging Microbes and Infections |
| spelling | doaj-art-2c74df388ccd4c65b2eeb1750e9646e22025-08-20T03:17:32ZengTaylor & Francis GroupEmerging Microbes and Infections2222-17512019-01-0181707910.1080/22221751.2018.1559708Chikungunya virus in Asia – Pacific: a systematic reviewB. M. C. Randika Wimalasiri-Yapa0Liesel Stassen1Xiaodong Huang2Louise M. Hafner3Wenbiao Hu4Gregor J. Devine5Laith Yakob6Cassie C. Jansen7Helen M. Faddy8Elvina Viennet9Francesca D. Frentiu10Institute of Health and Biomedical Innovation, School of Biomedical Sciences, Queensland University of Technology, Brisbane, QLD, AustraliaInstitute of Health and Biomedical Innovation, School of Biomedical Sciences, Queensland University of Technology, Brisbane, QLD, AustraliaInstitute of Health and Biomedical Innovation, School of Biomedical Sciences, Queensland University of Technology, Brisbane, QLD, AustraliaInstitute of Health and Biomedical Innovation, School of Biomedical Sciences, Queensland University of Technology, Brisbane, QLD, AustraliaInstitute of Health and Biomedical Innovation, School of Public Health and Social Work, Queensland University of Technology, Brisbane, QLD, AustraliaMosquito Control Laboratory, QIMR Berghofer Medical Research Institute, Brisbane, QLD, AustraliaDepartment of Disease Control, Faculty of Infectious & Tropical Diseases, The London School of Hygiene & Tropical Medicine, London, UKCommunicable Diseases Branch, Department of Health, Queensland Government, Herston, QLD, AustraliaResearch and Development, Australian Red Cross Blood Service, Brisbane, QLD, AustraliaResearch and Development, Australian Red Cross Blood Service, Brisbane, QLD, AustraliaInstitute of Health and Biomedical Innovation, School of Biomedical Sciences, Queensland University of Technology, Brisbane, QLD, AustraliaChikungunya virus (CHIKV) is a mosquito-borne pathogen that causes an acute febrile syndrome and severe, debilitating rheumatic disorders in humans that may persist for months. CHIKV’s presence in Asia dates from at least 1954, but its epidemiological profile in the region remains poorly understood. We systematically reviewed CHIKV emergence, epidemiology, clinical features, atypical manifestations and distribution of virus genotypes, in 47 countries from South East Asia (SEA) and the Western Pacific Region (WPR) during the period 1954–2017. Following the Cochrane Collaboration guidelines, Pubmed and Scopus databases, surveillance reports available in the World Health Organisation (WHO) and government websites were systematically reviewed. Of the 3504 records identified, 461 were retained for data extraction. Although CHIKV has been circulating in Asia almost continuously since the 1950s, it has significantly expanded its geographic reach in the region from 2005 onwards. Most reports identified in the review originated from India. Although all ages and both sexes can be affected, younger children and the elderly are more prone to severe and occasionally fatal forms of the disease, with child fatalities recorded since 1963 from India. The most frequent clinical features identified were arthralgia, rash, fever and headache. Both the Asian and East-Central-South African (ECSA) genotypes circulate in SEA and WPR, with ECSA genotype now predominant. Our findings indicate a substantial but poorly documented burden of CHIKV infection in the Asia-Pacific region. An evidence-based consensus on typical clinical features of chikungunya could aid in enhanced diagnosis and improved surveillance of the disease.https://www.tandfonline.com/doi/10.1080/22221751.2018.1559708Arbovirusmosquitoemerging virusalphavirusviral arthritis |
| spellingShingle | B. M. C. Randika Wimalasiri-Yapa Liesel Stassen Xiaodong Huang Louise M. Hafner Wenbiao Hu Gregor J. Devine Laith Yakob Cassie C. Jansen Helen M. Faddy Elvina Viennet Francesca D. Frentiu Chikungunya virus in Asia – Pacific: a systematic review Emerging Microbes and Infections Arbovirus mosquito emerging virus alphavirus viral arthritis |
| title | Chikungunya virus in Asia – Pacific: a systematic review |
| title_full | Chikungunya virus in Asia – Pacific: a systematic review |
| title_fullStr | Chikungunya virus in Asia – Pacific: a systematic review |
| title_full_unstemmed | Chikungunya virus in Asia – Pacific: a systematic review |
| title_short | Chikungunya virus in Asia – Pacific: a systematic review |
| title_sort | chikungunya virus in asia pacific a systematic review |
| topic | Arbovirus mosquito emerging virus alphavirus viral arthritis |
| url | https://www.tandfonline.com/doi/10.1080/22221751.2018.1559708 |
| work_keys_str_mv | AT bmcrandikawimalasiriyapa chikungunyavirusinasiapacificasystematicreview AT lieselstassen chikungunyavirusinasiapacificasystematicreview AT xiaodonghuang chikungunyavirusinasiapacificasystematicreview AT louisemhafner chikungunyavirusinasiapacificasystematicreview AT wenbiaohu chikungunyavirusinasiapacificasystematicreview AT gregorjdevine chikungunyavirusinasiapacificasystematicreview AT laithyakob chikungunyavirusinasiapacificasystematicreview AT cassiecjansen chikungunyavirusinasiapacificasystematicreview AT helenmfaddy chikungunyavirusinasiapacificasystematicreview AT elvinaviennet chikungunyavirusinasiapacificasystematicreview AT francescadfrentiu chikungunyavirusinasiapacificasystematicreview |