1,2,4-triazole-3-carboxamides induces G2/M cell cycle arrest in ovarian cancer cell lines

1,2,4-triazole-3-carboxamides induces G2/M cell cycle arrest in ovarian cancer cell lines

Introduction. Ovarian cancer is one of the most common gynecological cancers worldwide, which is difficult to diagnose and treat. the high mortality rate from ovarian cancer makes the development of new therapeutic drugs relevant. Ribavirin (RBV), commonly used antiviral agent, revealed the anticanc...

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Main Authors: E. M. Zhidkova, L. E. Grebenkina, V. P. Maksimova, D. D. Grigoreva, E. A. Mikhina, A. V. Matveev, M. G. Yakubovskaya, E. A. Lesovaya
Format: Article
Language:Russian
Published: Russian Academy of Sciences, Tomsk National Research Medical Center 2025-01-01
Series:Сибирский онкологический журнал
Subjects:
ovarian cancer
ribavirin
chemotherapy
1,2,4-triazole-3-carboxamides
cell cycle
apoptosis
Online Access:https://www.siboncoj.ru/jour/article/view/3357
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