COMBINATION THERAPY WITH BISOPROLOL AND AMLODIPINE IN TREATMENT OF ARTERIAL HYPERTENSION PATIENTS WITH CHRONIC OBSTRUCTIVE PULMONARY DISEASE
Aim. To evaluate the effectiveness of fixed combination of bisoprolol and amlodipine in arterial hypertension (AH) with chronic obstructive pulmonary disease (COPD).Material and methods. The study of 38 patients performed with AH of 1-2 grades and COPD of the 2nd grade of severity, in remission. As...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | Russian |
| Published: |
«SILICEA-POLIGRAF» LLC
2015-08-01
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| Series: | Кардиоваскулярная терапия и профилактика |
| Subjects: | |
| Online Access: | https://cardiovascular.elpub.ru/jour/article/view/175 |
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| Summary: | Aim. To evaluate the effectiveness of fixed combination of bisoprolol and amlodipine in arterial hypertension (AH) with chronic obstructive pulmonary disease (COPD).Material and methods. The study of 38 patients performed with AH of 1-2 grades and COPD of the 2nd grade of severity, in remission. As antihypertensive drug the combination of bisoprolol and amlodipine was used. At the baseline and in 12 weeks of therapy the patients underwent 24-hour blood pressure monitoring (ABPM), echocardiography (EchoCG), spirometry.Results. In 12 weeks of therapy 34 (89,5%) patients continued taking the drug. Therapy led to target BP values in 32 (84,2%) of patients with average daily dosage 7,5/10 mg. ABPM analysis demonstrates the stability of antihypertensive effect and significant improvement of the parameters in long-term usage of bisoprolol+amlodipine. At the background of treatment there was tendency for normalization of diastolic heart function. In evaluation of spirometry tests before and after 12 weeks of therapy there were no any significant differences in values that means absence of negative influence of combination drug on bronchial conduction.Conclusion. The results confirm the significance of combination therapy usage in AH with COPD. |
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| ISSN: | 1728-8800 2619-0125 |