Whole Genome Sequencing Shows a Low Proportion of Tuberculosis Disease Is Attributable to Known Close Contacts in Rural Malawi.

Whole Genome Sequencing Shows a Low Proportion of Tuberculosis Disease Is Attributable to Known Close Contacts in Rural Malawi.

<h4>Background</h4>The proportion of tuberculosis attributable to transmission from close contacts is not well known. Comparison of the genome of strains from index patients and prior contacts allows transmission to be confirmed or excluded.<h4>Methods</h4>In Karonga District...

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Main Authors: Judith R Glynn, José Afonso Guerra-Assunção, Rein M G J Houben, Lifted Sichali, Themba Mzembe, Lorrain K Mwaungulu, J Nimrod Mwaungulu, Ruth McNerney, Palwasha Khan, Julian Parkhill, Amelia C Crampin, Taane G Clark
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0132840
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