Glycylglycine promotes the solubility and antigenic utility of recombinant HCV structural proteins in a point-of-care immunoassay for detection of active viremia

Glycylglycine promotes the solubility and antigenic utility of recombinant HCV structural proteins in a point-of-care immunoassay for detection of active viremia

Abstract Background Although E. coli is generally a well-opted platform for the overproduction of recombinant antigens as heterologous proteins, the optimization of expression conditions to maximize the yield of functional proteins remains empirical. Herein, we developed an optimized E. coli (BL21)-...

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Main Authors: Heba Shawky, Ashraf A. Tabll, Reem M. Elshenawy, Naiera M. Helmy, Rehab I. Moustafa, Yasser K. Elesnawy, Marwa M. Abdelghany, Yasmine S. El-Abd
Format: Article
Language:English
Published: BMC 2024-01-01
Series:Microbial Cell Factories
Subjects:
Glycylglycine
E. coli (BL21)
Chaperone
HCV
Enzyme immunoassay
Core
Online Access:https://doi.org/10.1186/s12934-024-02297-1
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https://doi.org/10.1186/s12934-024-02297-1

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