Retention of the Native Epigenome in Purified Mammalian Chromatin.

Retention of the Native Epigenome in Purified Mammalian Chromatin.

A protocol is presented for the isolation of native mammalian chromatin as fibers of 25-250 nucleosomes under conditions that preserve the natural epigenetic signature. The material is composed almost exclusively of histones and DNA and conforms to the structure expected by electron microscopy. All...

Full description

Saved in:
Bibliographic Details
Main Authors: Andreas H Ehrensberger, Don-Marc Franchini, Philip East, Roger George, Nik Matthews, Sarah L Maslen, Jesper Q Svejstrup
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0133246
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items

Similar Items