Sensitive diagnosis of paucibacillary tuberculosis with targeted next-generation sequencing: a molecular diagnostic study

Abstract Background Targeted next-generation sequencing (tNGS) enables high-performance tuberculosis (TB) diagnosis and drug resistance prediction directly from clinical samples. However, its applicability to paucibacillary TB, including pediatric TB and extrapulmonary TB (EPTB), has been less explo...

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Bibliographic Details
Main Authors: Yu Chen, Lichao Fan, Zhong Ren, Yanhong Yu, Jiao Sun, Miaoran Wang, Chang Liu, Ying Zhang, Shuihua Lu, Xuhui Liu, Zhen Huang
Format: Article
Language:English
Published: BMC 2025-03-01
Series:BMC Medicine
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Online Access:https://doi.org/10.1186/s12916-025-03996-1
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