Pyroptosis in Endothelial Cells and Extracellular Vesicle Release in Atherosclerosis via NF-κB-Caspase-4/5-GSDM-D Pathway

Pyroptosis in Endothelial Cells and Extracellular Vesicle Release in Atherosclerosis via NF-κB-Caspase-4/5-GSDM-D Pathway

<b>Background</b>: Pyroptosis, an inflammatory cell death, is involved in the progression of atherosclerosis. Pyroptosis in endothelial cells (ECs) and its underlying mechanisms in atherosclerosis are poorly understood. Here, we investigated the role of a caspase-4/5-NF-κB pathway in pyr...

Full description

Saved in:
Bibliographic Details
Main Authors: Salman Shamas, Razia Rashid Rahil, Laveena Kaushal, Vinod Kumar Sharma, Nissar Ahmad Wani, Shabir H. Qureshi, Sheikh F. Ahmad, Sabry M. Attia, Mohammad Afzal Zargar, Abid Hamid, Owais Mohmad Bhat
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Pharmaceuticals
Subjects:
endothelial cells
pyroptosis
atherosclerosis
inflammasome
endothelial dysfunction
inflammation
Online Access:https://www.mdpi.com/1424-8247/17/12/1568
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://www.mdpi.com/1424-8247/17/12/1568

Similar Items