Impact of Gender, Age, and Obesity on Childhood Obstructive Sleep Apnea: A Cross-Sectional Study of 4,668 Children
Guimin Huang,1,* Qian Wang,2,3,* Li Chang,4 Siyu Ye,2 Junting Liu,1 Yingxia Lu,2 Tao Li,1 Xiaojun Zhan,2 Jieqiong Liang,2 Yijing Cheng,1 Qinglong Gu2,3 1Child Health Big Data Research Center, Capital Institute of Pediatrics, Beijing, People’s Republic of China; 2Department of...
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Dove Medical Press
2025-06-01
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| author | Huang G Wang Q Chang L Ye S Liu J Lu Y Li T Zhan X Liang J Cheng Y Gu Q |
| author_facet | Huang G Wang Q Chang L Ye S Liu J Lu Y Li T Zhan X Liang J Cheng Y Gu Q |
| author_sort | Huang G |
| collection | DOAJ |
| description | Guimin Huang,1,* Qian Wang,2,3,* Li Chang,4 Siyu Ye,2 Junting Liu,1 Yingxia Lu,2 Tao Li,1 Xiaojun Zhan,2 Jieqiong Liang,2 Yijing Cheng,1 Qinglong Gu2,3 1Child Health Big Data Research Center, Capital Institute of Pediatrics, Beijing, People’s Republic of China; 2Department of Otolaryngology-Head and Neck Surgery, Capital Institute of Pediatrics, Beijing, People’s Republic of China; 3Graduate School of Peking Union Medical College, Beijing, People’s Republic of China; 4Department of Respiratory Medicine, Capital Institute of Pediatrics, Beijing, People’s Republic of China*These authors contributed equally to this workCorrespondence: Qinglong Gu, Department of Otolaryngology-Head and Neck Surgery, Children’s Hospital, Capital Institute of Pediatrics, Beijing, People’s Republic of China, Email gql71@163.comPurpose: Obstructive sleep apnea (OSA) is a common condition in children, linked to significant health risks. However, the impact of gender, age, and obesity on OSA severity remains poorly understood. This study aimed to explore how these factors influence OSA in pediatric patients.Patients and Methods: This cross-sectional study was conducted at the Sleep Center of the Children’s Hospital Affiliated with the Capital Institute of Pediatrics from January 2017 to May 2023. We included children aged 0 to 15 years diagnosed with OSA via overnight polysomnography (PSG). Demographic data, including gender, age, and body measurements, were collected. The apnea-hypopnea index (AHI) and oxygen desaturation index (ODI) were recorded. Data analysis included one-way ANOVA for continuous variables, chi-square tests for proportions, linear trend analysis for changes across age and OSA severity, and Pearson/partial correlations for associations between BMI, AHI, and other variables.Results: The study involved 4668 children, with a mean age of 5.3 years, 62.3% of whom were boys. Boys had the highest Apnea-Hypopnea Index (AHI) (8.8 ± 7.9). The 0– 2 years age group exhibited the highest AHI (10.7 ± 9.8), while the obese group had the highest AHI (13.9 ± 19.8). Logistic regression analysis revealed that male gender (OR = 1.2, 95% CI: 1.11– 1.43), age 0– 2 years (OR = 1.49, 95% CI: 1.09– 2.04), and obesity (OR = 1.29, 95% CI: 1.09– 1.52) were significantly associated with moderate to severe OSA.Conclusion: This study underscores the complex roles of gender, age, and obesity in pediatric OSA severity. Boys, especially those in the 0– 2 years age group, had more severe OSA than girls, and obesity exacerbated OSA severity. These findings may guide improved screening and management strategies for pediatric OSA.Keywords: pediatric obstructive sleep apnea, age, gender, obesity, severity |
| format | Article |
| id | doaj-art-1a6d80db5929466da43efe69fd68c2c8 |
| institution | Kabale University |
| issn | 1179-1608 |
| language | English |
| publishDate | 2025-06-01 |
| publisher | Dove Medical Press |
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| series | Nature and Science of Sleep |
| spelling | doaj-art-1a6d80db5929466da43efe69fd68c2c82025-08-20T03:32:36ZengDove Medical PressNature and Science of Sleep1179-16082025-06-01Volume 17Issue 113911404103966Impact of Gender, Age, and Obesity on Childhood Obstructive Sleep Apnea: A Cross-Sectional Study of 4,668 ChildrenHuang G0Wang Q1Chang L2Ye S3Liu J4Lu Y5Li T6Zhan X7Liang J8Cheng Y9Gu Q10Child Health Big Data Research CenterDepartment of Otolaryngology-Head and Neck SurgeryDepartment of Respiratory MedicineDepartment of Otolaryngology-Head and Neck SurgeryChild Health Big Data Research CenterDepartment of Otolaryngology-Head and Neck SurgeryChild Health Big Data Research CenterDepartment of Otolaryngology-Head and Neck SurgeryDepartment of Otolaryngology-Head and Neck SurgeryChild Health Big Data Research CenterDepartment of Otolaryngology-Head and Neck SurgeryGuimin Huang,1,* Qian Wang,2,3,* Li Chang,4 Siyu Ye,2 Junting Liu,1 Yingxia Lu,2 Tao Li,1 Xiaojun Zhan,2 Jieqiong Liang,2 Yijing Cheng,1 Qinglong Gu2,3 1Child Health Big Data Research Center, Capital Institute of Pediatrics, Beijing, People’s Republic of China; 2Department of Otolaryngology-Head and Neck Surgery, Capital Institute of Pediatrics, Beijing, People’s Republic of China; 3Graduate School of Peking Union Medical College, Beijing, People’s Republic of China; 4Department of Respiratory Medicine, Capital Institute of Pediatrics, Beijing, People’s Republic of China*These authors contributed equally to this workCorrespondence: Qinglong Gu, Department of Otolaryngology-Head and Neck Surgery, Children’s Hospital, Capital Institute of Pediatrics, Beijing, People’s Republic of China, Email gql71@163.comPurpose: Obstructive sleep apnea (OSA) is a common condition in children, linked to significant health risks. However, the impact of gender, age, and obesity on OSA severity remains poorly understood. This study aimed to explore how these factors influence OSA in pediatric patients.Patients and Methods: This cross-sectional study was conducted at the Sleep Center of the Children’s Hospital Affiliated with the Capital Institute of Pediatrics from January 2017 to May 2023. We included children aged 0 to 15 years diagnosed with OSA via overnight polysomnography (PSG). Demographic data, including gender, age, and body measurements, were collected. The apnea-hypopnea index (AHI) and oxygen desaturation index (ODI) were recorded. Data analysis included one-way ANOVA for continuous variables, chi-square tests for proportions, linear trend analysis for changes across age and OSA severity, and Pearson/partial correlations for associations between BMI, AHI, and other variables.Results: The study involved 4668 children, with a mean age of 5.3 years, 62.3% of whom were boys. Boys had the highest Apnea-Hypopnea Index (AHI) (8.8 ± 7.9). The 0– 2 years age group exhibited the highest AHI (10.7 ± 9.8), while the obese group had the highest AHI (13.9 ± 19.8). Logistic regression analysis revealed that male gender (OR = 1.2, 95% CI: 1.11– 1.43), age 0– 2 years (OR = 1.49, 95% CI: 1.09– 2.04), and obesity (OR = 1.29, 95% CI: 1.09– 1.52) were significantly associated with moderate to severe OSA.Conclusion: This study underscores the complex roles of gender, age, and obesity in pediatric OSA severity. Boys, especially those in the 0– 2 years age group, had more severe OSA than girls, and obesity exacerbated OSA severity. These findings may guide improved screening and management strategies for pediatric OSA.Keywords: pediatric obstructive sleep apnea, age, gender, obesity, severityhttps://www.dovepress.com/impact-of-gender-age-and-obesity-on-childhood-obstructive-sleep-apnea--peer-reviewed-fulltext-article-NSSpediatric obstructive sleep apneaagegenderobesityseverity |
| spellingShingle | Huang G Wang Q Chang L Ye S Liu J Lu Y Li T Zhan X Liang J Cheng Y Gu Q Impact of Gender, Age, and Obesity on Childhood Obstructive Sleep Apnea: A Cross-Sectional Study of 4,668 Children Nature and Science of Sleep pediatric obstructive sleep apnea age gender obesity severity |
| title | Impact of Gender, Age, and Obesity on Childhood Obstructive Sleep Apnea: A Cross-Sectional Study of 4,668 Children |
| title_full | Impact of Gender, Age, and Obesity on Childhood Obstructive Sleep Apnea: A Cross-Sectional Study of 4,668 Children |
| title_fullStr | Impact of Gender, Age, and Obesity on Childhood Obstructive Sleep Apnea: A Cross-Sectional Study of 4,668 Children |
| title_full_unstemmed | Impact of Gender, Age, and Obesity on Childhood Obstructive Sleep Apnea: A Cross-Sectional Study of 4,668 Children |
| title_short | Impact of Gender, Age, and Obesity on Childhood Obstructive Sleep Apnea: A Cross-Sectional Study of 4,668 Children |
| title_sort | impact of gender age and obesity on childhood obstructive sleep apnea a cross sectional study of 4 668 children |
| topic | pediatric obstructive sleep apnea age gender obesity severity |
| url | https://www.dovepress.com/impact-of-gender-age-and-obesity-on-childhood-obstructive-sleep-apnea--peer-reviewed-fulltext-article-NSS |
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