Acceptance, Safety, and Effect Sizes in Online Dialectical Behavior Therapy for Borderline Personality Disorder: Interventional Pilot Study

BackgroundThe potential of telehealth psychotherapy (ie, the online delivery of treatment via a video web-based platform) is gaining increased attention. However, there is skepticism about its acceptance, safety, and efficacy for patients with high emotional and behavioral dy...

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Main Authors: Ruben Vonderlin, Tali Boritz, Carola Claus, Büsra Senyüz, Saskia Mahalingam, Rachel Tennenhouse, Stefanie Lis, Christian Schmahl, Jürgen Margraf, Tobias Teismann, Nikolaus Kleindienst, Shelley McMain, Martin Bohus
Format: Article
Language:English
Published: JMIR Publications 2025-01-01
Series:JMIR Formative Research
Online Access:https://formative.jmir.org/2025/1/e66181
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author Ruben Vonderlin
Tali Boritz
Carola Claus
Büsra Senyüz
Saskia Mahalingam
Rachel Tennenhouse
Stefanie Lis
Christian Schmahl
Jürgen Margraf
Tobias Teismann
Nikolaus Kleindienst
Shelley McMain
Martin Bohus
author_facet Ruben Vonderlin
Tali Boritz
Carola Claus
Büsra Senyüz
Saskia Mahalingam
Rachel Tennenhouse
Stefanie Lis
Christian Schmahl
Jürgen Margraf
Tobias Teismann
Nikolaus Kleindienst
Shelley McMain
Martin Bohus
author_sort Ruben Vonderlin
collection DOAJ
description BackgroundThe potential of telehealth psychotherapy (ie, the online delivery of treatment via a video web-based platform) is gaining increased attention. However, there is skepticism about its acceptance, safety, and efficacy for patients with high emotional and behavioral dysregulation. ObjectiveThis study aims to provide initial effect size estimates of symptom change from pre- to post treatment, and the acceptance and safety of telehealth dialectical behavior therapy (DBT) for individuals diagnosed with borderline personality disorder (BPD). MethodsA total of 39 individuals meeting the DSM-5 (Diagnostic and Statistical Manual of Mental Disorders [Fifth Edition]) criteria for BPD received 1 year of outpatient telehealth DBT at 3 sites in Germany and Canada. Effect size estimates were assessed using pre-post measures of BPD symptoms, dissociation, and quality of life. Safety was evaluated by analyzing suicide attempts and self-harm. Additionally, acceptance and feasibility, satisfaction with treatment, useability of the telehealth format, and the quality of the therapeutic alliance were assessed from both therapists’ and patients’ perspectives. All analyses were conducted on both the intention-to-treat (ITT) and according-to-protocol (ATP) samples. ResultsAnalyses showed significant and large pre-post effect sizes for BPD symptoms (d=1.13 in the ITT sample and d=1.44 in the ATP sample; P<.001) and for quality of life (d=0.65 in the ITT sample and d=1.24 in the ATP sample). Dissociative symptoms showed small to nonsignificant reductions. Self-harm behaviors decreased significantly from 80% to 28% of all patients showing at least 1 self-harm behavior in the last 10 weeks (risk ratio 0.35). A high dropout rate of 38% was observed. One low-lethality suicide attempt was reported. Acceptance, feasibility, and satisfaction measures were high, although therapists reported only moderate useability of the telehealth format. ConclusionsTelehealth DBT for BPD showed large pre-post effect sizes for BPD symptoms and quality of life. While the telehealth format appeared feasible and well-accepted, the dropout rate was relatively high. Future research should compare the efficacy of telehealth DBT with in-person formats in randomized controlled trials. Overall, telehealth DBT might offer a potentially effective alternative treatment option, enhancing treatment accessibility. However, strategies for decreasing drop-out should be considered. Trial RegistrationGerman Clinical Trials Register DRKS00027824; https://drks.de/search/en/trial/DRKS00027824
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spelling doaj-art-1860494480f24d6d9c0f83b7e723159c2025-01-14T21:01:12ZengJMIR PublicationsJMIR Formative Research2561-326X2025-01-019e6618110.2196/66181Acceptance, Safety, and Effect Sizes in Online Dialectical Behavior Therapy for Borderline Personality Disorder: Interventional Pilot StudyRuben Vonderlinhttps://orcid.org/0000-0003-4570-5648Tali Boritzhttps://orcid.org/0000-0002-6066-5624Carola Claushttps://orcid.org/0009-0001-6079-6632Büsra Senyüzhttps://orcid.org/0000-0002-9674-3655Saskia Mahalingamhttps://orcid.org/0009-0008-3221-9193Rachel Tennenhousehttps://orcid.org/0009-0001-5851-3912Stefanie Lishttps://orcid.org/0000-0002-8051-2756Christian Schmahlhttps://orcid.org/0000-0003-0141-0821Jürgen Margrafhttps://orcid.org/0000-0001-5207-7016Tobias Teismannhttps://orcid.org/0000-0002-6498-7356Nikolaus Kleindiensthttps://orcid.org/0000-0002-1696-2488Shelley McMainhttps://orcid.org/0000-0002-0269-5876Martin Bohushttps://orcid.org/0000-0002-1768-3608 BackgroundThe potential of telehealth psychotherapy (ie, the online delivery of treatment via a video web-based platform) is gaining increased attention. However, there is skepticism about its acceptance, safety, and efficacy for patients with high emotional and behavioral dysregulation. ObjectiveThis study aims to provide initial effect size estimates of symptom change from pre- to post treatment, and the acceptance and safety of telehealth dialectical behavior therapy (DBT) for individuals diagnosed with borderline personality disorder (BPD). MethodsA total of 39 individuals meeting the DSM-5 (Diagnostic and Statistical Manual of Mental Disorders [Fifth Edition]) criteria for BPD received 1 year of outpatient telehealth DBT at 3 sites in Germany and Canada. Effect size estimates were assessed using pre-post measures of BPD symptoms, dissociation, and quality of life. Safety was evaluated by analyzing suicide attempts and self-harm. Additionally, acceptance and feasibility, satisfaction with treatment, useability of the telehealth format, and the quality of the therapeutic alliance were assessed from both therapists’ and patients’ perspectives. All analyses were conducted on both the intention-to-treat (ITT) and according-to-protocol (ATP) samples. ResultsAnalyses showed significant and large pre-post effect sizes for BPD symptoms (d=1.13 in the ITT sample and d=1.44 in the ATP sample; P<.001) and for quality of life (d=0.65 in the ITT sample and d=1.24 in the ATP sample). Dissociative symptoms showed small to nonsignificant reductions. Self-harm behaviors decreased significantly from 80% to 28% of all patients showing at least 1 self-harm behavior in the last 10 weeks (risk ratio 0.35). A high dropout rate of 38% was observed. One low-lethality suicide attempt was reported. Acceptance, feasibility, and satisfaction measures were high, although therapists reported only moderate useability of the telehealth format. ConclusionsTelehealth DBT for BPD showed large pre-post effect sizes for BPD symptoms and quality of life. While the telehealth format appeared feasible and well-accepted, the dropout rate was relatively high. Future research should compare the efficacy of telehealth DBT with in-person formats in randomized controlled trials. Overall, telehealth DBT might offer a potentially effective alternative treatment option, enhancing treatment accessibility. However, strategies for decreasing drop-out should be considered. Trial RegistrationGerman Clinical Trials Register DRKS00027824; https://drks.de/search/en/trial/DRKS00027824https://formative.jmir.org/2025/1/e66181
spellingShingle Ruben Vonderlin
Tali Boritz
Carola Claus
Büsra Senyüz
Saskia Mahalingam
Rachel Tennenhouse
Stefanie Lis
Christian Schmahl
Jürgen Margraf
Tobias Teismann
Nikolaus Kleindienst
Shelley McMain
Martin Bohus
Acceptance, Safety, and Effect Sizes in Online Dialectical Behavior Therapy for Borderline Personality Disorder: Interventional Pilot Study
JMIR Formative Research
title Acceptance, Safety, and Effect Sizes in Online Dialectical Behavior Therapy for Borderline Personality Disorder: Interventional Pilot Study
title_full Acceptance, Safety, and Effect Sizes in Online Dialectical Behavior Therapy for Borderline Personality Disorder: Interventional Pilot Study
title_fullStr Acceptance, Safety, and Effect Sizes in Online Dialectical Behavior Therapy for Borderline Personality Disorder: Interventional Pilot Study
title_full_unstemmed Acceptance, Safety, and Effect Sizes in Online Dialectical Behavior Therapy for Borderline Personality Disorder: Interventional Pilot Study
title_short Acceptance, Safety, and Effect Sizes in Online Dialectical Behavior Therapy for Borderline Personality Disorder: Interventional Pilot Study
title_sort acceptance safety and effect sizes in online dialectical behavior therapy for borderline personality disorder interventional pilot study
url https://formative.jmir.org/2025/1/e66181
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