Catalpol promotes hippocampal neurogenesis and synaptogenesis in rats after multiple cerebral infarctions by mitochondrial regulation: involvement of the Shh signaling pathway

Catalpol promotes hippocampal neurogenesis and synaptogenesis in rats after multiple cerebral infarctions by mitochondrial regulation: involvement of the Shh signaling pathway

IntroductionIschemic stroke greatly threatens human life and health. Neuro-restoration is considered to be the critical points in reestablishing neurological function and improving the quality of life of patients. Catalpol is the main active ingredient of the Chinese herbal medicine Dihuang, which h...

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Bibliographic Details
Main Authors: Zishan Huang, Feng Li, Xiaoyu Zheng, Jiarui Zheng, Yilei Dong, Zhao Ding, Huanyu Gou, Mingjiang Yao, Jianxun Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-12-01
Series:Frontiers in Pharmacology
Subjects:
catalpol
Shh signaling pathway
mitochondria
cerebral infarction
neuro-restoration
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2024.1461279/full
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https://www.frontiersin.org/articles/10.3389/fphar.2024.1461279/full

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