P671: Enhancing genetic diagnostics: The critical role of enzyme activity assays and RNA-sequencing as primary multi-omics screening tools - Mandy Radefeldt; Erick Alberto Rivera Comparan; Christian Beetz; Tobias Boettcher; Sabrina Lemke; Catarina Pereira; Sebastian Oppermann; Claudia Mrosowski; Susan Zielske; Peter Bauer (Genetics in Medicine Open)