Serum concentrations of levosimendan and its metabolites OR-1855 and OR-1896 in cardiac surgery patients with cardiopulmonary bypass

Serum concentrations of levosimendan and its metabolites OR-1855 and OR-1896 in cardiac surgery patients with cardiopulmonary bypass

BackgroundThe inotropic drug levosimendan is often used as an individualized therapeutic approach perioperatively in cardiac surgery patients with cardiopulmonary bypass (CPB). Data regarding serum concentrations of levosimendan and its metabolites within this context is lacking.MethodsIn this retro...

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Bibliographic Details
Main Authors: Hannah Kipka, Uwe Liebchen, Max Hübner, Georg Höfner, Otto Frey, Klaus T. Wanner, Erich Kilger, Christian Hagl, Roland Tomasi, Hanna Mannell
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-08-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
levosimendan
OR-1896
OR-1855
cardiac insufficiency
cardiopulmonary bypass
serum levels
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2024.1406338/full
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