Combination of Periodontal Ligament Stem Cells and Metformin via Organic Cation Transporters for Periodontal Regeneration in Rats

Combination of Periodontal Ligament Stem Cells and Metformin via Organic Cation Transporters for Periodontal Regeneration in Rats

Periodontal regeneration remains challenging due to individual variability, especially in treatments involving bioactive factors such as metformin. This study aimed to investigate the role of organic cation transporters (OCTs) in metformin-induced periodontal regeneration. The expression and functio...

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Bibliographic Details
Main Authors: Qingchen Qiao, Zeqing Zhao, Yaxi Sun, Jing Wang, Xiaowei Li, Li Zhang, Hao Yang, Ning Zhang, Ke Zhang, Yuxing Bai
Format: Article
Language:English
Published: MDPI AG 2025-05-01
Series:Biomolecules
Subjects:
organic cation transporters
human periodontal ligament stem cells
metformin
osteogenesis
cementogenesis
periodontal regeneration
Online Access:https://www.mdpi.com/2218-273X/15/5/663
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