Virulence and Replicative Fitness of HIV-1 Transmitted/Founder (T/F) Viruses Harbouring Drug Resistance-Associated Mutation

Virulence and Replicative Fitness of HIV-1 Transmitted/Founder (T/F) Viruses Harbouring Drug Resistance-Associated Mutation

The biological characteristics of early transmitted/founder (T/F) variants are crucial factors for viral transmission and constitute key determinants for the development of better therapeutics and vaccine strategies. The present study aimed to generate T/F viruses and to characterize their biologica...

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Bibliographic Details
Main Authors: Aanand Sonawane, Deepak Selvam, Ling Yue, Manohar Nesakumar, Sandhya Vivekanandan, Manickam Ashokkumar, Eric Hunter, Luke Elizabeth Hanna
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Viruses
Subjects:
HIV
transmitted/founder virus
infectious molecular clones
NNRTI resistance
Online Access:https://www.mdpi.com/1999-4915/16/12/1854
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https://www.mdpi.com/1999-4915/16/12/1854

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