Associations of peripheral blood lymphopenia to disease course, treatment and TNF-α in sarcoidosis

Associations of peripheral blood lymphopenia to disease course, treatment and TNF-α in sarcoidosis

Abstract Background Severe sarcoidosis has been associated with peripheral blood (PB) total lymphopenia and high tumour necrosis factor α (TNF-α) levels, and the lymphopenia phenotype seems to respond poorly to conventional treatment. However, the mechanisms behind PB lymphopenia and its correlation...

Full description

Saved in:
Bibliographic Details
Main Authors: Avinash Padhi, Anders Eklund, Clas Malmeström, Elina Erikson, Gustav Hallén, Anna Smed-Sörensen, Susanna Kullberg
Format: Article
Language:English
Published: BMC 2025-04-01
Series:Respiratory Research
Subjects:
Sarcoidosis
Lymphopenia
Treatment
TNF-α
B-cells
T-cells
Online Access:https://doi.org/10.1186/s12931-025-03212-x
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doi.org/10.1186/s12931-025-03212-x

Similar Items