Context Matters: Divergent Roles of Exercise-Induced and Tumor-Derived Lactate in Cancer

Context Matters: Divergent Roles of Exercise-Induced and Tumor-Derived Lactate in Cancer

Instead of being waste product of metabolism, lactate, has become a key metabolic and signaling molecule in both exercise physiology and tumor biology. Carcinogenic cells produce huge amounts of lactate through the Warburg effect, which is a hallmark of aggressive tumors, increasing acidity in the e...

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Bibliographic Details
Main Authors: Amir hossein Ahmadi Hekmatikar, Ghazal Zolfaghari, Aref Basereh, D. Maryama Awang Daud, Kayvan Khoramipour
Format: Article
Language:English
Published: MDPI AG 2025-07-01
Series:Biomolecules
Subjects:
lactate
exercise
cancer
metabolism
Online Access:https://www.mdpi.com/2218-273X/15/7/1010
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