Engineering a Dual-Function Starch–Cellulose Composite for Colon-Targeted Probiotic Delivery and Synergistic Gut Microbiota Regulation in Type 2 Diabetes Therapeutics

Engineering a Dual-Function Starch–Cellulose Composite for Colon-Targeted Probiotic Delivery and Synergistic Gut Microbiota Regulation in Type 2 Diabetes Therapeutics

<b>Objectives:</b> This study engineered a colon-targeted drug delivery system (CTDS) using the dual pharmaceutical and edible properties of <i>Pueraria lobata</i> to encapsulate <i>Lactobacillus paracasei</i> for Type 2 diabetes mellitus (T2DM) therapy. <b>...

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Bibliographic Details
Main Authors: Ruixiang Liu, Yikang Ding, Yujing Xu, Qifeng Wu, Yanan Chen, Guiming Yan, Dengke Yin, Ye Yang
Format: Article
Language:English
Published: MDPI AG 2025-05-01
Series:Pharmaceutics
Subjects:
colon-targeted drug delivery
probiotic encapsulation
starch–cellulose composite
microbiota–metabolic axis
pharmaceutical material engineering
Online Access:https://www.mdpi.com/1999-4923/17/5/663
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