Distinct Thalamo‐Subcortical Circuits Underlie Painful Behavior and Depression‐Like Behavior Following Nerve Injury

Distinct Thalamo‐Subcortical Circuits Underlie Painful Behavior and Depression‐Like Behavior Following Nerve Injury

Abstract Clinically, chronic pain and depression often coexist in multiple diseases and reciprocally reinforce each other, which greatly escalates the difficulty of treatment. The neural circuit mechanism underlying the chronic pain/depression comorbidity remains unclear. The present study reports t...

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Main Authors: Jie Deng, Li Chen, Cui‐Cui Liu, Meng Liu, Guo‐Qing Guo, Jia‐You Wei, Jian‐Bo Zhang, Hai‐Ting Fan, Zi‐Kun Zheng, Pu Yan, Xiang‐Zhong Zhang, Feng Zhou, Sui‐Xiang Huang, Ji‐Feng Zhang, Ting Xu, Jing‐Dun Xie, Wen‐Jun Xin
Format: Article
Language:English
Published: Wiley 2024-09-01
Series:Advanced Science
Subjects:
chronic pain
comorbidity
depression
nucleus accumbens
paraventricular thalamus anterior
paraventricular thalamus posterior
Online Access:https://doi.org/10.1002/advs.202401855
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