Identification of cuproptosis-related genes in chronic apical periodontitis based on bulk and single-cell RNA sequencing analyses and experimental validation

Identification of cuproptosis-related genes in chronic apical periodontitis based on bulk and single-cell RNA sequencing analyses and experimental validation

BackgroundChronic apical periodontitis (CAP) is a prevalent oral inflammatory disease, yet the complex mechanisms underlying its etiology remain unclear. A recently identified cell death pathway known as cuproptosis may be linked to this condition.MethodsDifferentially expressed cuproptosis-related...

Full description

Saved in:
Bibliographic Details
Main Authors: Caiyi Zhang, Jie Zhao, Keqing Pan, Lingshuang Liu, Mengyu Jiao, Changqing Yuan, Chunyan Wan
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-08-01
Series:Frontiers in Immunology
Subjects:
cuproptosis
chronic apical periodontitis
single-cell RNA sequencing
copper homeostasis imbalance
cell-cell communication
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1559220/full
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items

Similar Items